Alginate Oligosaccharides
Alginate oligosaccharides (AOS) are short chains of sugar molecules derived from alginate, a natural polysaccharide found in brown algae. They have gained attention for their diverse biological activities and potential applications in various fields, including medicine, agriculture, cosmetics and functional foods. AOS are characterized by their low molecular weight, high water solubility, and ability to induce various biological responses.
Alginate oligosaccharides (AOS) are typically produced by enzymatic hydrolysis of alginate. Alginate oligosaccharides are composed of repeating units of mannuronic acid (M) and guluronic acid (G), linked by β-1,4-glycosidic bonds. They can be categorized into mannuronate oligosaccharides (MAOS), guluronate oligosaccharides (GAOS), and heterozygous mannuronate and guluronate oligosaccharides (HAOS).
AOS can act as plant immunity inducers, enhancing resistance to pathogens and abiotic stresses like drought and salinity. They trigger various defense responses, including the production of reactive oxygen species (ROS), calcium influx, stomata closure, and callose deposition.

Alginate oligosaccharides (AOS), derived from alginate, offer various benefits in cosmetics due to their prebiotic, antioxidant, anti-inflammatory, and moisturizing properties. They can enhance skin hydration, protect against photoaging, and potentially help with conditions like atopic dermatitis and acne by modulating skin microbiota and immune responses.
Alginate oligosaccharides can act as prebiotics, selectively feeding beneficial bacteria in the skin's microbiome, promoting a healthier skin ecosystem. They can improve skin's water-holding capacity and reduce transepidermal water loss, leading to better hydration.
Alginate oligosaccharides can help reduce inflammation in the skin, potentially alleviating conditions like atopic dermatitis and acne. They can protect the skin from oxidative damage caused by free radicals, which contributes to premature aging. Alginate oligosaccharides can offer protection against the harmful effects of UV radiation, helping to prevent photoaging. Some studies suggest that Alginate oligosaccharides may promote wound healing by stimulating cell growth and tissue repair. Alginate oligosaccharides can potentially reduce melanin production, which may lead to a skin-whitening effect. Alginate oligosaccharides can contribute to a stronger skin barrier, improving the skin's ability to protect itself from external aggressors.

Alginate oligosaccharides can influence the gut microbiota, which in turn can affect skin health through the gut-skin axis.They can modulate the immune system, helping to regulate inflammation and immune responses in the skin.Alginate oligosaccharides can influence the production and signaling of metabolites by the skin's microbiome, contributing to skin health.
Due to their diverse benefits, Alginate oligosaccharides are used as active ingredients in skincare products like moisturizers, serums, and anti-aging creams. Sodium alginate, a precursor to Alginate oligosaccharides, is used as a thickener, gelling agent, stabilizer, and emulsifier in various cosmetic products, including shampoos and creams. The effectiveness of Alginate oligosaccharides in cosmetics can depend on the concentration used and the overall formulation of the product.
Key Technical Parameters
|
Appearance |
Light yellow amorphous powder |
|
Alginate Oligosaccharides |
≥90% |
|
pH (1:50) |
4.5-6.5 |
|
Lead |
≤5.0 mg/kg |
|
Arsenic |
≤3.0 mg/kg |
|
Cadmium |
≤3.0 mg/kg |
|
Mercury |
≤3.0 mg/kg |
Applications
● Anti-acne effect
● Anti-aging effect
● Antimicrobial effec
● Moisturizing effect
● Anti-inflammatory effect
● Antioxidant effect
Advantages
● Natural source
● Lower blood sugar
● Prevent Alzheimer's disease
● Suppress cancer cells
● Immune Regulation
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