Recombinant Type III Collagen Liquid Raw Materials (GAE)

Product Name: Recombinant Type III Collagen Liquid Raw Materials (GAE)
INCI Name: Sh-Polypeptide-123,Water, Glycerin,1,2-Hexanediol
Product Code: YNR®GAE
Protein Content 1%
Functions: Anti-aging,Nourishing,Anti-wrinkle, Skin repairing,

Product Detail

product details

product description

GAE is a Bio-fermented Type III Collagen Liquid Raw Material with a 1% protein content, making it highly compatible with various products and easy to use.It is widely used in various skincare and makeup products. Vegan collagen (liquid) derived from Pichia pastoris yeast using patented high-density fermentation, high efficient separation and purification process.

内容插图-Recombinant Type III Collagen Liquid Raw Materials (GAE)-1

GAE is a colorless or lightly yellow transparent liquid. The main ingredient Sh-polypeptide-123 is a highly purified type III human-like collagen, obtained by yeast fermentation. GAE is widely used in cosmetic and medical beauty product. As a cosmetic ingredient, the recommended amount is 0.5%~15%. Sh-polypeptide-123 is an anti-aging recombinant (recombined protein) human peptide used in skin care that’s created through fermenting a form of yeast called Pichia pastoris (AKA Komagataella pastoris). It’s a biomimetic ingredient that resembles the human collagen alpha-1 (III) chain, a crucial component of type 3 collagen, the second most abundant type in skin.

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Recombinant human peptides are exciting ingredients touted to support healthy collagen production and tensile strength, resulting in a visible reduction in the appearance of fine lines and wrinkles, a decrease in visible skin laxity, improved skin firmness, smoother skin and improved hydration.

Chemists use bioengineering practices to extract a “code” for a desired DNA sequence into a vector, a particle that can replicate in a host cell. In the case of sh-polypeptide-123, this is the code for collagen alpha-1 (III). Then, this vector containing code is introduced into a host cell (for sh-polypeptide-123, it’s Pichia pastoris yeast cells) and fermented. These host cells are then purified and prepared for use in cosmetics as well as supplements. Sh-Polypeptide-123 is often used in serums, sheet masks, anti-aging creams, concentrated boosters and post-procedure soothing gels where it works alongside humectants and antioxidants to reinforce the skin’s surface.

Key Technical Parameters

Appearance	Colorless or light yellow transparent liquid
Odor	Odorless
Solid content(g/L)	≥10.0
RHC purity /%	≥90.0
pH(1mg/mL )	5.0-7.0
Relative density(20℃/20℃)	1.07±0.02
Heat resistant	If kept at 40℃±1℃ for 24h, no obvious differences are found when returned to room temperature
Cold resistant	If kept at -8℃±2℃ for 24h, no obvious differences are found when returned to room temperature
Pb(mg/kg)	≤10
As(mg/kg)	≤2
Hg(mg/kg)	≤1
Cd(mg/kg)	≤5
Total aerobic count (cfu/g)	≤100
Mold and Yeast (cfu/g)	≤100
Thermotolerant coliform bacteria	Negative
Pseudomonas aeruginosa	Negative
Staphylococcus aureus	Negative