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Natural antioxidant Anti-inflammatory citrus extract cosmetic active ingredient Hesperidin

Natural Ingredients

Hesperidin

Hesperidin is a flavonoid derived from citrus fruits that has antioxidant and anti-inflammatory properties. Hesperidin is often used in anti-aging, anti-inflammatory, skin whitening products in cosmetic.

 

  • Product Name: Hesperidin
  • INCI Name: Hesperidin
  • Product Code: YNR®HP
  • CAS No.: 520-26-3
  • Formula: C28H34O15
  • Functions: Antioxidant, Brightening, Anti-inflammatory

Product Introduction

Hesperidin is a flavanone glycoside (flavonoid) found abundantly in citrus fruits. Its aglycone form is called hesperetin. Hesperidin is believed to play a role in plant defense. Hesperidin has antioxidant, anti inflammatory, hypolipidemic, vasoprotective and anticarcinogenic and cholesterol lowering actions. Hesperidin can inhibit following enzymes: Phospholipase A2, lipoxygenase, HMG CoA reductase and cyclo-oxygenase. Hesperidins improve the health of capillaries by reducing the capillary permeability. Hesperidin are used to reduce hay fever and other allergic conditions by inhibiting the release of histamine from mast cells. The possible anti cancer activity of hesperidin could be explained by the inhibition of polyamine synthesis.

Also known as lemon peel extract or orange peel extract, hesperidin is a natural occurring flavonoid that occurs within citrus fruits (more specifically in the actual peels of lemons and oranges). In skin care, Hesperidin appears as either a white or colorless crystalline structure. Hesperidin can provide antioxidant and soothing properties that together contribute towards a brightened and improved skin appearance.

Hesperidin’s antioxidant protection helps to neutralize free-radicals present in the environment. This helps to lower levels of reactive oxygen species found in the skin, which may work to promote skin radiance. When topically applied, hesperidin also exhibits a soothing effect and reinforces the skin’s permeability barrier. As a result, skincare products, such as creams and ointments, often infuse hesperidin into formulation to help alleviate dry skin.

hesperidin antioxidant

Hesperidin is a flavanone glycoside (flavonoid) (C28H34O15) found abundantly in citrus fruits. Its aglycone form is called hesperetin. Hesperidin is believed to play a role in plant defense. It acts as an antioxidant. 

The Value of Hesperidin in the Cosmetics Industry:

Anti-aging and skin barrier enhancement: Hesperidin is used in anti-aging products due to its antioxidant properties, helping to strengthen the skin barrier and protect the skin from environmental damage.

 Anti-UV damage: Hesperidin can effectively prevent UV-induced skin cell lipid peroxidation, thereby reducing erythema and UV damage to the skin.

Whitening and depigmentation: Hesperidin exhibits whitening effects by inhibiting tyrosinase activity and melanin synthesis. Studies have shown that hesperidin can dose-dependently reduce tyrosinase activity and melanin content in melanocytes.

•Wound healing: Hesperidin has the potential to promote wound healing, which makes it promising for treating skin damage and accelerating recovery.

Anti-inflammatory effects: Due to its anti-inflammatory properties, hesperidin can be used to treat inflammatory skin diseases such as acne.

Prevention of skin cancer and other skin diseases: Hesperidin’s anti-cancer properties make it a potential application value in preventing skin cancer and other skin diseases.

Active ingredients in cosmetics: As a natural compound, hesperidin has good application prospects as an active ingredient in cosmetics due to its stability and low toxicity.

Sustainable skin care products: As a byproduct of orange peel, hesperidin meets the needs of sustainable skin care products and helps promote sustainable strategies based on the circular economy.

Key Technical Parameters

Appearance

Yellow-Brown powder

Assay

≥90.0%

Loss on dry

5.0% max

Sulphated Ash

0.5% max

Arsenic

1.0 ppm max

Mercury

0.1 ppm max

Cadmium

1.0 ppm max

Lead

3.0 ppm max

Total aerobic microbial count

≤1000 cfu/g max

Total yeasts and molds count

100 cfu/g max

E.Coli

  Negative

Salmonella

  Negative

Coliforms

 ≤10 cfu/g

Hesperidin, also known as vitamin P, is a flavonoid substance widely found in citrus fruits. Its chemical structure is a dihydroflavonoid oxygen glycoside structure, which is weakly acidic, slightly bitter, and difficult to dissolve in water. Most of hesperidin exists in the waste of citrus processing, such as peel and fruit capsule. The content of hesperidin is the highest in mature peel and tissue, and the content is lower in juice and citrus capsules.

Effects of Hesperidin in skin care:

Antioxidant Properties: Hesperidin Scavenges free radicals and reduces oxidative stress in the skin.

Anti-inflammatory: Hesperidin helps to calm irritated skin and reduce inflammation.

Hesperidin skin lightening

Vasoprotective Effects: Hesperidin strengthens capillaries and improves microcirculation, which can reduce dark circles and under-eye puffiness.


Hesperidin is used in skincare for their potent antioxidant and anti-inflammatory properties. It helps protect the skin from oxidative stress, reduce inflammation, and improve microcirculation, contributing to a more even skin tone and healthier complexion. Hesperidin is often found in skin lightening products to treat dark spots, circles under the eyes, and hyperpigmentation.

Applications

 Antioxidant

 Anti-aging

 Anti-inflammatory

 Anti-UV Damage

 Skin whitening

Advantages

  High purity

  Natural source

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