Biotech Breakthrough: Schizophyllan Emerges as Skincare Star

Tianjin,China – August 5,2025 – YR Chemspec, a leader in scientifically advanced skincare solutions, today spotlights Schizophyllan,Schizophyllan (also known as Sizofiran in cosmetic ingredient directories) is a natural β-glucan extracted from the Schizophyllum commune fungus.This substance possesses a unique molecular structure: a β-(1-3)-D-glucan with glucose as its sole component, featuring a β-(1-6) glucoside branch linked to every three glucose molecules.It is this distinctive structure that grants it exceptional skincare efficacy.

In nature, Schizophyllum commune is sometimes found growing alongside shiitake mushrooms and is an edible fungus. Scientists have discovered that the polysaccharide extracted from this unassuming fungus exhibits remarkable potential in skincare.Laboratory studies confirm the substance operates through a triple skincare mechanism: deep hydration, anti-inflammatory soothing, and antioxidant defense.

Beyond Moisture: Upgraded Multi-Functional Skincare

Schizophyllan's value extends far beyond basic hydration. Modern research continues to reveal its multi-faceted efficacy:

• Exceptional Moisturizing Performance: By maintaining stratum corneum hydration, Schizophyllan's moisturizing effect surpasses traditional hyaluronic acid under stressful conditions. Experimental data shows that even at concentrations as low as 0.1%-0.4%, it significantly boosts skin hydration.

• Antioxidant Protection: Schizophyllan is an outstanding antioxidant, effectively neutralizing skin damage from air pollutants like harmful substances in secondhand smoke. Marubi's R&D team discovered that the antioxidant activity of Schizophyllan-fermented pueraria (kudzu root) extract is substantially higher than that of the individual components.

• Anti-Aging & Repair Capabilities: By promoting skin cell proliferation and collagen synthesis, Schizophyllan helps delay skin aging. Its ability to combat UV damage and accelerate post-sun recovery also makes it a comprehensive protective ingredient.

• Anti-Inflammatory & Soothing Properties: Schizophyllan effectively inhibits phospholipase A2 activity (a key enzyme in the production of inflammatory and allergic mediators), thereby reducing skin inflammation and allergic reactions.

Safety Application: Scientific Assurance for Natural Ingredients

As consumer focus on cosmetic safety intensifies, positive news emerges regarding Schizophyllan's safety assessment. According to the latest safety assessment report, Schizophyllan is included in China's Inventory of Existing Cosmetic Ingredients (2021 Edition) (Entry No. 04326).

Its maximum historical usage level in leave-on cosmetics reaches 2.5%, and the assessment concludes that "this ingredient will not cause harm to human health under normal, reasonable, and foreseeable conditions of use."

Studies show Schizophyllan is non-irritating to skin and eyes, with no reports of sensitization. It also lacks phototoxicity and photosensitivity. With a molecular weight of approximately 100,000, it is readily soluble in cold water, and its aqueous solution has a neutral pH, allowing easy incorporation into various cosmetic formulations.

Schizophyllum commune, once an obscure forest fungus, is now shining with new glory in the beauty and wellness sectors through the power of science. It exemplifies the perfect fusion of natural ingredients and biotechnology, offering a new paradigm for implementing sustainability principles within the cosmetics industry. In the symphony of technology and nature, Schizophyllan is composing a new movement for the beauty sector.

About YR Chemspec:
YR Chemspec is dedicated to developing high-performance skincare solutions rooted in scientific innovation and proven efficacy. We combine cutting-edge research with rigorously tested ingredients to empower individuals to achieve their healthiest, most radiant skin. Our commitment to quality, transparency, and skin health guides everything we do.

For specifications, technical data sheets, and formulation support, please contact our sales team by email: sales2@yrspec.com