Natural Preservative ε-Polylysine Revolutionizes Beauty and Personal Care Industry, Emerging as a Safe and Efficient Rising Star

Tianjin,China – July 29,2025 – YR Chemspec, a leader in scientifically advanced skincare solutions, today spotlights ε-Polylysine.Amid surging consumer demand for "clean beauty" and product safety, ε-Polylysine (ε-PL)—a bioactive compound derived from microbial fermentation—is rapidly gaining prominence in the beauty and personal care sector. This natural polymer offers a revolutionary solution for cosmetic preservation systems, thanks to its exceptional antibacterial properties, biodegradability, and human biocompatibility.

Core Advantages: Safety, Broad-Spectrum Efficacy, Stability

1. Ultra-Safe Natural Antimicrobial Agent

   • Multiple toxicological studies confirm that ε-Polylysine decomposes into lysine (an essential amino acid) within the human body, eliminating accumulation toxicity. Experiments show that even at daily intakes as high as 5g/kg body weight, organisms exhibit only transient mild reactions, with no long-term carcinogenic or mutagenic risks.

   • Its safety profile far exceeds traditional preservatives (e.g., phenoxyethanol, formaldehyde releasers), making it ideal for sensitive skin and mother-infant products.

2. Broad-Spectrum Antimicrobial Action in Extreme Conditions

   • Demonstrates significant efficacy against Gram-positive bacteria (e.g., Staphylococcus aureus), Gram-negative bacteria (e.g., E. coli), fungi, and molds, with a remarkably low minimum inhibitory concentration (MIC) of ≤100μg/mL.

   • Exceptional thermal stability (retains full activity after 20min at 120°C) and maintains high performance across acidic/alkaline environments, ensuring compatibility with diverse formulations.

3. Dual Functionality: Preservation + Repair

   • Beyond antimicrobial effects, its cationic properties enhance product penetration and active ingredient absorption. Complexes formed with metal ions (zinc/copper) deliver nutritional supplementation and antioxidant benefits, supporting anti-aging and barrier repair.

Application Breakthroughs: From Oral Care to Efficacy Cosmetics

1. Oral Health Innovations

   • H. pylori Infection Treatment: Clinical trials reveal that ε-Polylysine-containing mouthwash achieves an 81.9% oral H. pylori clearance rate after two months, offering a novel approach to oral microbiome regulation.

   • Replaces chemical biocides in toothpaste and mouthwash, reducing mucosal irritation while inhibiting pathogenic biofilm formation.

2. Skincare & Makeup Advancements

   • Replaces traditional preservative systems, solving contamination challenges in water-based products (emulsions, creams) and extending post-opening shelf life.

   • Synergistic effects with glycine or acetic acid boost antimicrobial efficacy by >50%, reducing overall additive usage.

3. Hygiene Product Upgrades

   • As a core component of superabsorbent polymers, it inhibits bacterial growth in sanitary pads and baby diapers, minimizing odor and skin inflammation risks.

Combination with Lipid-Soluble Vitamin C Derivatives: Synergistic Brightening & Antioxidant Effects

ε-PL + Ascorbyl Tetraisopalmitate (VC-IP)

• Synergistic Mechanism:

  • VC-IP (with 16.5× higher penetration than standard Vitamin C) is stabilized by ε-PL through microbial/metal ion inhibition;

  • ε-PL suppresses tyrosinase activity, blocking melanin synthesis signals, while VC-IP reduces existing pigment – forming a "prevention + reversal" brightening pathway.

Conclusion: Redefining "Safe & Effective" Industry Standards

ε-Polylysine’s rise marks the industrialization of "non-toxic preservation,"It transcends being a preservative alternative—it bridges efficacy and safety, pioneering new pathways for infant, medical aesthetics, and green cosmetics.

About YR Chemspec:
YR Chemspec is dedicated to developing high-performance skincare solutions rooted in scientific innovation and proven efficacy. We combine cutting-edge research with rigorously tested ingredients to empower individuals to achieve their healthiest, most radiant skin. Our commitment to quality, transparency, and skin health guides everything we do.

For specifications, technical data sheets, and formulation support, please contact our sales team by email: sales2@yrspec.com