Ergothioneine

Ergothioneine (EGT) is a naturally occurring, potent amino acid with unique antioxidant properties. Recognized for its role in protecting cells from oxidative stress and promoting healthy aging, it is increasingly featured in advanced dietary supplements designed to support long-term wellness at the most fundamental level.

Product Name: Ergothioneine
Product Code: YNR®EGT
CAS No.: 497-30-3
Formula: C9H15N3O2S

Product Detail

product details

product description

Ergothioneine (EGT) is a unique, sulfur-bearing amino acid that functions as a highly stable antioxidant. Unlike many other antioxidants, the human body cannot produce Ergothioneine; it must be acquired through dietary sources like mushrooms, grains, and meats, or via supplementation. Scientific interest in Ergothioneine is largely due to its exceptional ability to travel throughout the body and accumulate precisely in tissues and organs most vulnerable to oxidative damage, making it a key subject in nutritional science and preventive health.

Potent and Stable Antioxidant: Ergothioneine effectively neutralizes harmful reactive oxygen species (ROS) and free radicals. A key advantage is its stability; unlike some antioxidants, it does not become a pro-oxidant, ensuring reliable and safe protection.
Mitochondrial Support: It accumulates within mitochondria, the cellular powerhouses, protecting them from oxidative stress and thereby supporting efficient energy production, which is vital for overall vitality.

Anti-Inflammatory & Healthy Aging: By reducing oxidative stress—a primary driver of chronic inflammation—Ergothioneine helps modulate the body's inflammatory response. This action supports joint health, cognitive function, and overall wellness. Furthermore, by protecting fundamental cellular components like DNA, proteins, and lipids from cumulative oxidative damage, Ergothioneine is recognized as a crucial nutrient for promoting healthy aging and sustaining long-term cellular resilience.

Key Technical Parameters

Appearance	White Powder
Assay	98.0% min
Loss on dry	0.5% max
Heavy metals(Pb)	20 ppm max
Arsenic(As2O3)	2.0 ppm max
Lead(Pb)	1.0 ppm max
Mercury(Hg)	0.1 ppm max
Cadmium(Cd)	0.5 ppm max

Mechanism of Action of Ergothioneine
The unique effectiveness of Ergothioneine is rooted in its specialized transport system. A specific protein transporter (OCTN1) actively shuttles Ergothioneine from the bloodstream into cells that are under high metabolic or oxidative stress, such as those in the brain, liver, and eyes. This ensures targeted delivery to areas of greatest need. Once inside the cell, its distinct molecular structure allows it to powerfully and safely neutralize various oxidants without producing harmful byproducts. This combination of intelligent transport and stable antioxidant activity forms the scientific foundation for EGT's role in a comprehensive health regimen.